SEPTEMBER, 2012 Gene-Related Patents Issued - Full patent
CHEMICAL APPARATUS
Pat No Title Assignee Date Issued Country
8,257,666 Integrated active flux microfluidic devices and methods California Institute of Technology 4-Sep-12 United States
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,268,594 pyrC as a selection marker in Escherichia coli Advanced Accelerator Applications S.A. 18-Sep-12 France
8,257,927 Hereditary hemochromatosis gene Bio-Rad Laboratories, Inc. 4-Sep-12 United States
8,268,568 Methods and compositions for categorizing patients Case Western Reserve University 18-Sep-12 United States
8,268,622 EPSPS mutants Cibus US LLC 18-Sep-12 United States
8,257,922 Method of profiling gene expression in a subject having alzheimer's disease GeneNews Corporation 4-Sep-12 United States
8,273,534 Predictors of patient response to treatment with EGF receptor inhibitors Genomic Health, Inc. 25-Sep-12 United States
8,273,568 Replication-competent herpes simplex virus mediates destruction of neoplastic cells Georgetown University 25-Sep-12 United States
8,268,597 Recombinant microorganism and method for producing L-lysine Global Bio-Chem Technology Group Company Limited 18-Sep-12 Hong Kong
8,268,609 Production of sialylated N-glycans in lower eukaryotes Glycofi, Inc. 18-Sep-12 United States
8,257,945 Identification of eukaryotic internal ribosome entry site (IRES) elements Icon Genetics, Inc. 4-Sep-12 United States
8,263,346 Nonhuman model animal lacking the ability to control lymphocyte migration Japan Science and Technology Agency 11-Sep-12 Japan
8,257,920 Method of detecting activation of notch signal transmission system Keio University 4-Sep-12 Japan
8,257,941 Methods and platforms for drug discovery using induced pluripotent stem cells Kyoto University 4-Sep-12 Japan
8,268,583 Cell with improved secretion mediated by MrgA protein or homologue Novozymes A/S 18-Sep-12 Denmark
8,257,915 Farnesyltransferase inhibitors for treatment of laminopathies, cellular aging and atherosclerosis Progeria Research Foundation, Inc. 4-Sep-12 United States
8,257,972 Cell transformed by human Wnt3a gene Shiseido Company, Ltd. 4-Sep-12 Japan
8,268,610 Nucleic acids useful in the manufacture of oil Solazyme, Inc. 18-Sep-12 United States
8,257,969 Genetic suppression and replacement The Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth 4-Sep-12 Ireland
8,257,928 Methods for predicting and treating tumors resistant to drug, immunotherapy and radiation The Regents of the University of California 4-Sep-12 United States
8,268,619 Method for the isolation and expansion of cardiac stem cells from biopsy Universita Degli Studi di Roma "La Sapienza" 18-Sep-12 Italy
8,257,929 Gene expression profiling of Parkinson's Disease University of Miami 4-Sep-12 United States
8,257,919 Micro-RNA profiles associated with endometrial cancer development and response to cisplatin and doxorubicin chemotherapy University of South Florida 4-Sep-12 United States
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,271,202 Modified host bio-data management Fernandez; Dennis S. 18-Sep-12 United States
8,275,555 Method and system for comparative genomics International Business Machines Corporation 25-Sep-12 United States
8,265,879 Determination of single peak melting temperature by PCR analogy and double sigmoid equation Roche Molecular Systems, Inc. 11-Sep-12 United States
8,275,557 Computer-implemented method and computer-based system for validating DNA sequencing data SmartGene GmbH 25-Sep-12 Switzerland
8,265,880 Gene expression level analyzing method, gene expression level anlayzing program, and gene expression level analyzing device Sony Corporation 11-Sep-12 Japan
DRUG
Pat No Title Assignee Date Issued Country
8,268,799 Compositions and methods for inhibiting expression of the HAMP gene Alnylam Pharmaceuticals, Inc. 18-Sep-12 United States
8,258,100 Ligand/lytic peptide methods of use Board of Supervisors of Louisiana State University and Agricultural and Mechanical College 4-Sep-12 United States
8,263,659 Thyroid receptor ligands Bristol-Myers Squibb Company 11-Sep-12 United States
8,273,345 Targeted gene delivery to dendritic cells California Institute of Technology 25-Sep-12 United States
8,257,703 Anti-ganglioside antibodies and compositions Chugai Seiyaku Kabushiki Kaisha 4-Sep-12 Japan
8,263,573 Delivery of dsRNA to arthropods Commonwealth Scientific and Industrial Research Organisation 11-Sep-12 Australia
8,273,722 Enhanced biotherapeutic production using inhibitory RNA Dharmacon, Inc. 25-Sep-12 United States
8,257,737 Tissue implants and methods for making and using same Intini; Giuseppe 4-Sep-12 United States
8,263,649 Benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof Medifron DBT Co., Ltd. 11-Sep-12 Korea
8,258,120 9-substituted minocycline compounds Paratek Pharmaceuticals, Inc. 4-Sep-12 United States
8,273,344 Recombinant adeno-associated virus expressing human antisense gene CyP2J2 and its preparation methods Tongji Hospital 25-Sep-12 China P. Rep.
8,263,571 Gene silencing of the brother of the regulator of imprinted sites (BORIS) Vendevia Group, LLC 11-Sep-12 United States
8,263,068 Modified cells expressing a protein that modulates activity of bHLH proteins, and uses thereof Washington State University Research Foundation 11-Sep-12 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,273,955 Spontaneous nodulation in plants Aarhus Universitet 25-Sep-12 Denmark
8,273,956 Method for performing homologous recombination in plants Biogemma S.A.S. 25-Sep-12 France
8,273,951 Down-regulation of gene expression using artificial micrornas E. I. du Pont de Nemours and Company 25-Sep-12 United States
8,263,822 TREM-2 gene and protein as inhibitors of expression of GA733-2, and transgenic animals comprising the same and uses thereof GLO Biotech 11-Sep-12 Korea
8,273,953 Antisense DNA of sweetpotato expansin cDNA and method for increasing storage root yield using the same Korea University Industrial & Academic Collaboration Foundation 25-Sep-12 Korea
8,273,954 Genetically transformed plants Monsanto Technology LLC 25-Sep-12 United States
8,269,062 Lunaria annua, Cardamine graeca and Teesdalia nudicaulis FAE genes and their use in producing nervonic and eicosenoic acids in seed oils National Research Council of Canada 18-Sep-12 Canada
8,269,065 Nucleic acids and proteins associated with sucrose degradation in coffee Nestec, S.A. 18-Sep-12 Switzerland
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,268,962 Molecules for targeting compounds to various selected organs or tissues Prosensa Technologies B.V. 18-Sep-12 Netherlands
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,268,981 Plasmodium malariae and plasmodium ovale genes and uses thereof Abbott Laboratories 18-Sep-12 United States
8,273,870 Compositions and methods for inhibiting expression of a mutant gene Alnylam Pharmaceuticals, Inc. 25-Sep-12 United States
8,273,869 Lipid formulated dsRNA targeting the PCSK9 gene Alnylam Pharmaceuticals, Inc. 25-Sep-12 United States
8,263,761 Group of nucleic acid fragments for prevention of HIV infection or AIDS and the usage thereof Beijing Solobio Genetechnology Company Ltd. 11-Sep-12 China P. Rep.
8,258,287 Interfering RNAs targeting the morbillivirus nucleoprotein gene Centre de Cooperation Internationale en Recherche Agronomique pour le Developpment 4-Sep-12 France
8,263,756 Method of gene transfer via vascular system or ureter Chugai Seiyaku Kabushiki Kaisha 11-Sep-12 Japan
8,268,983 Primers for amplifying and detecting the beta 2 adrenergic receptor gene Council of Scientific & Industrial Research 18-Sep-12 United States
8,268,985 siRNA targeting amyloid beta (A4) precursor protein (APP) Dharmacon, Inc. 18-Sep-12 United States
8,268,979 Human MutY Human Genome Sciences, Inc. 18-Sep-12 United States
8,268,986 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Merck Sharp & Dohme Corp. 18-Sep-12 United States
8,273,866 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA) Merck Sharp & Dohme Corp. 25-Sep-12 United States
8,258,282 Isolated nucleic acid molecules from transgenic papaya line 16-0-1 resistant to papaya ringspot virus and use thereof National Chung Hsing University 4-Sep-12 Taiwan
8,258,285 RNA molecules and vectors for gene silencing Plant Bioscience Limited 4-Sep-12 United Kingdom
8,263,569 Gene silencing Plant Biosciences Limited 11-Sep-12 United Kingdom
8,263,760 Methods and means for treating DNA repeat instability associated genetic disorders Prosensa Holding BV 11-Sep-12 Netherlands
8,258,288 RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA) Sirna Therapeutics, Inc. 4-Sep-12 United States
8,263,759 Sets of probes and primers for the diagnosis of select cancers The United States of America, as Represented by the Secretary, Department of Health and Human Services 11-Sep-12 United States
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