OCTOBER, 2013 Gene-Related Patents Issued - Full patent: http://patft.uspto.gov/netahtml/PTO/srchnum.htm
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,546,143 Compositions and methods for inhibiting expression of a target gene Alnylam Pharmaceuticals, Inc. 1-Oct-13 United States
8,557,584 Preparing a homogenous population of stem cells committed to differentiated to a specific cell type Ao-Forschungsinstitut Davos 15-Oct-13 Switzerland
8,557,525 Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof Celera Corporation 15-Oct-13 United States
8,569,066 Genetically engineered recombinant Escherichia coli producing L-tryptophan having originally L-phenylalanine productivity, and method for producing L-tryptophan using the microorganism CJ Cheiljedang Corporation 29-Oct-13 Korea
8,557,547 Phosphotriesterase from agrobacterium radiobacter P230 Commonwealth Scientific and Industrial Research Organisation 15-Oct-13 Australia
8,546,120 Perhydrolase variant providing improved specific activity E. I. du Pont de Nemours and Company 1-Oct-13 United States
8,557,556 Perhydrolase variant providing improved specific activity E. I. du Pont de Nemours and Company 15-Oct-13 United States
8,546,119 Perhydrolase variant providing improved specific activity E. I. du Pont de Nemours and Company 1-Oct-13 United States
8,569,065 Compositions and methods for the delivery of biologically active RNAs EGEN, Inc. 29-Oct-13 United States
8,568,985 Breast endothelial cell expression patterns Genzyme Corporation 29-Oct-13 United States
8,569,054 Mammalian cell lines for increasing longevity and protein yield from a cell culture Immunomedics, Inc. 29-Oct-13 United States
8,563,270 Calcium-binding photoprotein, gene encoding the same, and use thereof JNC Corporation 22-Oct-13 Japan
8,546,079 Reporter gene construct, assay kit and detection method Kabushiki Kaisha Toshiba 1-Oct-13 Japan
8,569,038 Transformant having an increased frequency of homologous recombination Kikkoman Corporation 29-Oct-13 Japan
8,551,772 Detection of mutations in a gene associated with resistance to viral infection, OAS1 Kineta Two, LLC 8-Oct-13 United States
8,568,972 Substances causing differentiation Medicyte GmbH 29-Oct-13 Germany
8,557,550 Pyripyropene a biosynthetic gene Meija Seika Pharma Co., Ltd. 15-Oct-13 Japan
8,551,739 Method for molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase Memorial Sloan-Kettering Cancer Center 8-Oct-13 United States
8,569,051 Expression vector for gene therapy Mogam Biotechnology Research Institute 29-Oct-13 Korea
8,568,980 Nucleic acids, methods and kits for the diagnosis of DYT6 primary torsion dystonia Mount Sinai School of Medicine 29-Oct-13 United States
8,551,774 Expression vectors containing a truncated epstein barr nuclear antigen 1 lacking the Gly-Gly-Ala domain for enhanced transient gene expression National Research Council of Canada 8-Oct-13 Canada
8,569,029 DNase expression in recombinant host cells Novozymes A/S 29-Oct-13 Denmark
8,557,585 Fusion polynucleotide for biosynthesis of beta-carotene using bicistronic gene expression and method for producing beta-carotene using the same Republic of Korea, Rural Development Administration 15-Oct-13 Korea
8,551,773 Methods and compositions relating to improved lentiviral vectors and their applications Research Development Foundation 8-Oct-13 United States
8,563,314 Methods and compositions for modulating PD1 Sangamo BioSciences, Inc. 22-Oct-13 United States
8,551,718 Functional assay for 5-HT2A, histamine H1 or adrenergic alpha 1B receptors Suven Life Science Limited 8-Oct-13 India
8,551,700 Diagnostic and prognostic tests The Brigham and Women's Hospital, Inc. 8-Oct-13 United States
8,557,532 Diagnosis and treatment of drug-resistant Ewing'S sarcoma The University of Utah Research Foundation 15-Oct-13 United States
8,546,105 Engineering intracellular sialylation pathways The University of Wyoming 1-Oct-13 United States
8,546,125 Recombinant hosts and methods for manufacturing polyhydroxyalkanoate Tianjin Greenbio Material Co., Ltd. 1-Oct-13 China P Rep.
8,546,135 In vivo genome-wide mutagenesis University of Utah Research Foundation 1-Oct-13 United States
8,551,775 Subpopulations of spore-like cells and uses thereof VBI Technologies, L.L.C. 8-Oct-13 United States
8,551,734 Selection and enrichment of proteins using in vitro compartmentalization Zheng; Yu 8-Oct-13 United States
COMBINATORIAL CHEMISTRY TECHNOLOGY
Pat No Title Assignee Date Issued Country
8,557,745 Markers and methods for assessing and treating Crohn's and related disorders Janssen Biotech, Inc. 15-Oct-13 United States
8,557,742 Method of enhancing enzyme activity Novozymes A/S 15-Oct-13 Denmark
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,548,747 Optimizing genome-wide mutation analysis of chromosomes and genes Children's Hospital Medical Center of Akron 1-Oct-13 United States
8,566,039 Method and system to characterize transcriptionally active regions and quantify sequence abundance for large scale sequencing data Genomic Health, Inc. 22-Oct-13 United States
8,560,334 Method and arrangement for arranging an information service to determine nutrition and/or medication Lahteenmaki; Pertti 15-Oct-13 Finland
8,572,018 Method, system and software arrangement for reconstructing formal descriptive models of processes from functional/modal data using suitable ontology New York University 29-Oct-13 United States
DRUG
Pat No Title Assignee Date Issued Country
8,562,989 Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer Agensys, Inc. 22-Oct-13 United States
8,562,985 Antibodies to c-Met Amgen Fremont Inc. 22-Oct-13 United States
8,551,474 Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase Central Iowa Health System 8-Oct-13 United States
8,552,069 Method for treatment of obesity, dyslipidemia, fatty liver or insulin resistance syndrome comprising camphene as active ingredient Industry-Academic Cooperation Foundation, Yonsei University 8-Oct-13 Korea
8,557,246 Fusion protein that directs vaccine antigens to antigen-presenting cells, and applications thereof Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria 15-Oct-13 Spain
8,557,779 Cancer vaccine composition International Institute of Cancer Immunology, Inc. 15-Oct-13 Japan
8,568,745 Water-soluble drug carrier and process for producing the same Kyushu University, National University Corporation 29-Oct-13 Japan
8,563,520 Treatment of ocular disease with inhibitors of alpha2 macroglobulin protein McGill University 22-Oct-13 Canada
8,569,254 Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same National Yang Ming University 29-Oct-13 Taiwan
8,551,970 Genetic suppression and replacement Optigen Patents Limited 8-Oct-13 Ireland
8,557,875 Gene transfer agent composition containing polyamidoamine dendron Public University Corporation Osaka Prefecture University 15-Oct-13 Japan
8,551,945 Methods and compositions for treating neuropathies Sangamo BioSciences, Inc. 8-Oct-13 United States
8,568,708 Tumor-specific delivery of therapeutic agents via liposomase The John Hopkins University 29-Oct-13 United States
8,551,481 Anti-cancer vaccine composition comprising an anti-CD223 antibody and kit comprising an anti-cancer vaccine and an anti-CD223 antibody The Johns Hopkins University 8-Oct-13 United States
8,546,345 Compositions and methods for siRNA inhibition of angiogenesis The Trustees of the University of Pennsylvania 1-Oct-13 Canada
8,563,511 Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway University of Rochester 22-Oct-13 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,546,643 Pig model for atherosclerosis Aarhus Universitet 1-Oct-13 Denmark
8,546,647 Pathogen inducible plant thehalose-6-phophate phophatase gene promoters and regulatory elements BASF Plant Science GmbH 1-Oct-13 Germany
8,546,644 Recombinant gene which enhances the ability of fish to tolerate low dissolved oxygen stress and the use thereof Institute of Hydrobiology, Chinese Academy of Sciences (Wuhan, CN) 1-Oct-13 China P Rep.
8,569,579 BPMV-based viral constructs useful for VIGS and expression of heterologous proteins in legumes Iowa State University Research Foundation, Inc. 29-Oct-13 United States
8,552,256 Gene capable of being expressed specifically in endosperm of plant, promoter for the gene, and use of the gene and the promoter National Institute of Agrobiological Sciences 8-Oct-13 Japan
8,558,055 Genetically modified rat comprising a cytokine gene disruption and exhibiting a greater susceptibility to a cytokine-mediated autoimmune and/or inflammatory disease Transposagen Biopharmaceuticals, Inc. 15-Oct-13 United States
8,569,574 Methods and compositions for improved fertilization and embryonic survival Wisconsin Alumni Research Foundation 29-Oct-13 United States
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,569,454 YS68 polypeptide involved in primitive hematopoiesis Chugai Seiyaku Kabushiki Kaisha 29-Oct-13 Japan
8,546,540 Antibody targeting osteoclast-related protein Siglec-15 Daiichi Sankyo Company, Limited 1-Oct-13 Japan
8,563,684 Tumor antigen protein SART-3 and tumor antigen peptides thereof Green Peptide Co., Ltd. 22-Oct-13 Japan
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,546,554 Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene Alnylam Pharmaceuticals, Inc. 1-Oct-13 United States
8,569,469 B.sub.12-dependent dehydratases with improved reaction kinetics E I du Pont de Nemours and Company 29-Oct-13 United States
8,569,473 Pestivirus species Intervet International B.V. 29-Oct-13 Netherlands
8,569,474 Double stranded constructs comprising one or more short strands hybridized to a longer strand Isis Pharmaceuticals, Inc. 29-Oct-13 United States
8,552,169 Transcription factor-based biosensor The Regents of the University of California 8-Oct-13 United States
8,557,969 Compositions and methods for regulating cardiac performance The Regents of the University of Michigan 15-Oct-13 United States
8,557,515 Compositions and methods for cancer diagnosis and therapy Thomas Jefferson University 15-Oct-13 United States
8,551,971 Composition for treatment of pancreatic cancer Tokyo Women's Medical University 8-Oct-13 Japan
8,552,170 Expression vector for establishing highly productive cell and the highly productive cell Toyo Boseki Kabushiki Kaisha 8-Oct-13 Japan
8,552,171 RNA sequence-specific mediators of RNA interference University of Massachusetts 8-Oct-13 United States
8,569,471 Stem cell beacon University of South Florida 29-Oct-13 United States
SURGERY
Pat No Title Assignee Date Issued Country
8,551,069 Methods and apparatus for treating contrast nephropathy Medtronic Adrian Luxembourg S.a.r.l. 8-Oct-13 Luxembourg
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