MARCH, 2012 Gene-Related Patents Issued - Full patent
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,129,180 Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene An Educational Foundation Kinki University 6-Mar-12 United States
8,133,689 Members of the capsaicin/vanilloid receptor family of proteins and uses thereof Bayer Schering Pharma Aktiengesellschaft 13-Mar-12 Gerrmany
8,129,176 Integrated active flux microfluidic devices and methods California Institute of Technology 6-Mar-12 United States
8,129,110 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 6-Mar-12 Japan
8,129,109 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 6-Mar-12 Japan
8,129,108 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 6-Mar-12 Japan
8,133,668 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 13-Mar-12 Japan
8,137,953 Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells Cargill Inc. 20-Mar-12 United States
8,137,911 Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences CellScript, Inc. 20-Mar-12 United States
8,143,061 Industrial method for producing RNA and system for carrying out said method Centre National de la Recherche Scientifique 27-Mar-12 France
8,137,918 Sperm-specific cation channel, CatSper4, and uses therefor Children's Medical Center Corporation 20-Mar-12 United States
8,137,946 Recombinant GRAS strains expressing thermophilic arabinose isomerase as an active form and method of preparing food grade tagatose by using the same CJ Cheiljedang Corporation 20-Mar-12 Korea
8,137,907 Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof Cold Spring Harbor Laboratory 20-Mar-12 United States
8,137,966 Rat embryonic stem cell Dainippon Sumitomo Pharma Co., Ltd. 20-Mar-12 Japan
8,129,134 Methods of cleaving DNA with rationally-designed meganucleases Duke University 6-Mar-12 United States
8,133,697 Methods of cleaving DNA with rationally-designed meganucleases Duke University 13-Mar-12 United States
8,143,016 Methods of cleaving DNA with rationally-designed meganucleases Duke University 27-Mar-12 United States
8,143,015 Methods of cleaving DNA with rationally-designed meganucleases Duke University 27-Mar-12 United States
8,137,910 Method of regulating gene expression Duke University 20-Mar-12 United States
8,142,994 Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling Erasmus University Medical Center Rotterdam 27-Mar-12 Netherlands
8,143,032 Alleles of the thrA gene of Enterobacteriaceae Evonik Degussa GmbH 27-Mar-12 Gerrmany
8,133,714 Process for the fermentative preparation of organic chemical compounds using coryneform bacteria in which the SugR gene is present in attenuated form Evonik Degussa GmbH 13-Mar-12 Gerrmany
8,137,970 Methods for inducing the differentiation of hematopoietic stem cells into megakaryocytes and platelets, and gene controlling the differentiation Ewha University-Industry Collaboration Foundation 20-Mar-12 Korea
8,143,003 Method for detecting oral squamous-cell carcinoma Fujifilm Corporation 27-Mar-12 Japan
8,133,674 Method of profiling gene expression in a subject having diabetes GeneNews Corporation 13-Mar-12 United States
8,133,675 Method of profiling gene expression in a subject having an infectious disease GeneNews Corporation 13-Mar-12 United States
8,142,998 Osteoarthritis biomarkers and uses thereof GeneNews, Inc. 27-Mar-12 Canada
8,129,154 Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate Genomatica, Inc. 6-Mar-12 United States
8,137,963 Method for highly amplifying target gene in mammalian cell and vector therefor Hiroshima University 20-Mar-12 Japan
8,143,008 Method of nucleic acid amplification Illumina, Inc. 27-Mar-12 United States
8,137,916 Susceptibility gene for alzheimer's disease Isis Innovation Ltd. 20-Mar-12 United Kingdom
8,129,163 Gene suitable for alcohol dehydrogenase, vector and transformant Kaneka Corporation 6-Mar-12 Japan
8,129,144 Papilloma pseudovirus and preparation Loyola University Chicago 6-Mar-12 United States
8,143,024 Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection Merck Serono Biodevelopment 27-Mar-12 France
8,129,119 System for manipulating nucleic acids Modular Genetics, Inc. 6-Mar-12 United States
8,137,919 Method of determining the sensitivity of cancer cells to EGFR inhibitors including cetuximab, panitumumab and erlotinib Montefiore Medical Center 20-Mar-12 United States
8,129,181 F1B-TMIR plasmid vector and transgenic mouse National Health Research Institutes 6-Mar-12 Taiwan
8,143,007 Nested primer sets for amplifying mouse immunoglobulin variable gene segments National Institute of Immunology 27-Mar-12 India
8,129,122 Method of predicting metastasis of oral cavity cancer into cervical lymph node and diagnosis kit to be used in the prediction National Institute of Radiological Sciences 6-Mar-12 Japan
8,137,951 Methods for producing hyaluronan in a recombinant host cell Novozymes, Inc. 20-Mar-12 United States
8,129,125 Gene and protein expression profiles associated with the therapeutic efficacy of EGFR-TK inhibitors Nuclea Biotechnologies, Inc. 6-Mar-12 United States
8,129,112 Polymorphisms in the human CYP2D6 gene promoter region and their use in diagnostic and therapeutic applications PGxHealth, LLC 6-Mar-12 United States
8,143,002 Methods for isolating and characterizing endogenous mRNA-protein (mRNP) complexes Ribonomics, Inc. 27-Mar-12 United States
8,133,725 Bone marrow stromal cells comprising a nucleic acid encoding a notch intracellular domain SanBio, Inc. 13-Mar-12 United States
8,137,933 Mammalian expression vector pUHAB Schering Corporation 20-Mar-12 United States
8,129,120 Methods for genetic analysis of DNA to detect sequence variances Sequenom, Inc. 6-Mar-12 United States
8,133,678 COT102 insecticidal cotton Syngenta Participations AG 13-Mar-12 Switzerland
8,129,161 Bardet-Biedl susceptibility gene and uses thereof The University of Iowa Research Foundation 6-Mar-12 United States
8,143,038 Thermophilic micro-organisms for ethanol production TMO Renewables Limited 27-Mar-12 United Kingdom
8,137,962 Compositions for treating cystic fibrosis University of Florida Research Foundation 20-Mar-12 United States
8,137,914 Variants of alpha-fetoprotein coding and expression sequences University of North Carolina at Chapel Hill 20-Mar-12 United States
8,143,029 Methods and means related to diseases Valipharma 27-Mar-12 United Kingdom
8,143,009 Toxicity typing using liver stem cells VistaGen, Inc. 27-Mar-12 United States
8,137,947 Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator Voellmy; Richard 20-Mar-12 Switzerland
8,133,679 Methods of identifying agents that diminish cellular toxicity associated with an .alpha.-synuclein polypeptide of Parkinson's disease in yeast Whitehead Institute for Biomedical Research 13-Mar-12 United States
COMBINATORIAL CHEMISTRY TECHNOLOGY
Pat No Title Assignee Date Issued Country
8,138,123 Gene expressing analysis tool Takeda Pharmaceutical Company Limited 20-Mar-12 Japan
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,135,545 System and method for collecting data regarding broad-based neurotoxin-related gene mutation association Iverson Genetic Diagnostics, Inc. 13-Mar-12 United States
8,145,436 Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same The Trustees of the University of Pennsylvania 27-Mar-12 United States
8,131,475 Methods for identifying, diagnosing, and predicting survival of lymphomas The United States of America as represented by the Secretary, Department of Health and Human Services 6-Mar-12 United States
DRUG
Pat No Title Assignee Date Issued Country
8,133,873 Recombinant chemokine-antigen vaccine Cancer Institute, Chinese Academy of Medical Sciences 13-Mar-12 China P. Rep.
8,129,402 Screening molecules with anti-prion activity: kits, methods and screened molecules Centre National de la Recherche Scientifique 6-Mar-12 France
8,138,225 Histone deacetylase inhibitors based on alpha-ketoepoxide compounds Errant Gene Therapeutics, LLC 20-Mar-12 United States
8,129,355 Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex Intrexon Corporation 6-Mar-12 United States
8,142,770 Drug comprising as the active ingredient proliferative vector containing survivin promoter Kosai; Kenichiro 27-Mar-12 Japan
8,137,676 Genetically engineered equine influenza virus and uses thereof Mount Sinai School of Medicine 20-Mar-12 United States
8,129,354 Treatment of neurological disorders by dsRNA administration Novartis AG 6-Mar-12 Switzerland
8,143,229 Method for production of a transformed cell Qiagen GmbH 27-Mar-12 Gerrmany
8,143,232 Gene fusion targeted therapy The Regents of the University of Michigan 27-Mar-12 United States
8,128,921 Use of conditional plasmodium strains lacking nutrient transporters in malaria vaccination University of Connecticut 6-Mar-12 United States
8,137,662 Proliferated cell lines and uses thereof University of South Florida 20-Mar-12 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,134,046 Method for producing arachidonic acid and/or eicosapentaenoic acid in useful transgenic plants BASF Plant Science GmbH 13-Mar-12 Gerrmany
8,143,479 Plastidic phosphoglucomutase genes E I du Pont de Nemours and Company 27-Mar-12 United States
8,134,045 Protein involved in restoration of cytoplasmic male sterility to fertility and gene encoding the protein and gene Institut National de la Recherche Agronomique 13-Mar-12 France
8,143,478 Peptide transporting to chromoplasts in petals and method of constructing plant having yellowish petals by using the same Kirin Beer Kabushiki Kaisha 27-Mar-12 Japan
8,129,589 Protoporphyrinogen oxidase having activity of imparting resistance against acifluorfen and gene thereof Nippon Soda Co., Ltd. 6-Mar-12 Japan
8,143,484 Method for regulating agrobacterium-mediated transformation Pioneer Hi-Bred International, Inc. 27-Mar-12 United States
8,129,588 Regulatory sequences for expressing gene products in plant reproductive tissue Syngenta Participations AG 6-Mar-12 Switzerland
8,134,047 Maize plants with reduced gene silencing The Regents of the University of California 13-Mar-12 United States
8,138,391 Or gene and its use in manipulating carotenoid content and composition in plants and other organisms The United States of America as represented by the Secretary of Agriculture 20-Mar-12 United States
8,143,480 Compositions and methods for efficient gene silencing in plants Whitehead Institute for Biomedical Research 27-Mar-12 United States
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,133,974 Ferroportin1 nucleic acids, proteins, antibodies and methods Children's Medical Center Corporation 13-Mar-12 United States
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,143,390 Compositions and methods for inhibiting expression of anti-apoptotic genes Alnylam Pharmaceuticals, Inc. 27-Mar-12 United States
8,129,519 Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof Cholody; Wieslaw M. 6-Mar-12 United States
8,138,327 Inducible systems and methods for controlling siRNA expression City of Hope 20-Mar-12 United States
8,138,329 siRNA targeting connective tissue growth factor (CTGF) Dharmacon, Inc. 20-Mar-12 United States
8,143,413 Polycationized phospholipid derivatives Eisai R&D Management Co., Ltd. 27-Mar-12 Japan
8,129,514 Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same Evogene Ltd. 6-Mar-12 Israel
8,133,985 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same Panagene Inc. 13-Mar-12 Korea
8,143,384 Mutation of PRPS1 gene causing CMTX5 disease and the use thereof Sungkyunkwan University Foundation for Corporate Collaboration 27-Mar-12 Korea
8,129,510 Minigene expression cassette The Board of Trustees of the Leland Stanford Junior University 6-Mar-12 United States
8,129,356 Bmx mediated signal transduction in irradiated vascular endothelium Vanderbilt University 6-Mar-12 United States
8,138,324 Expression system for proteins Xbrane Bioscience AB 20-Mar-12 Sweden
PLANT PROTECTING AND REGULATING COMPOSITIONS
Pat No Title Assignee Date Issued Country
8,143,192 Methods for increasing the resistance of plants to hypoxic conditions Bayer Cropscience N.V. 27-Mar-12 Belgium
SURGERY
Pat No Title Assignee Date Issued Country
8,131,371 Methods and apparatus for monopolar renal neuromodulation Ardian, Inc. 6-Mar-12 United States
8,145,317 Methods for renal neuromodulation Ardian, Inc. 27-Mar-12 United States
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