JULY 2012 Gene-Related Patents Issued - Full patent
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,222,005 Method for gene identification signature (GIS) analysis Agency for Science, Technology and Research 17-Jul-12 Singapore
8,227,214 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA Ajinomoto Co., Inc. 24-Jul-12 Japan
8,222,007 L-glutamic acid producing bacterium and a method for producing L-glutamic acid Ajinomoto Co., Inc. 17-Jul-12 Japan
8,232,059 Method of identifying A. baumannii with OXA-131-like drug resistance in diabetic patients Alsultan; Abdulrahman A. 31-Jul-12 Saudi Arabia
8,232,051 Primer set for gene amplification, reagent for gene amplification including the same, and uses thereof ARKRAY, Inc. 31-Jul-12 Japan
8,232,081 Methods and microorganisms for production of panto-compounds BASF SE 31-Jul-12 Germany
8,221,976 Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification Becton, Dickinson and Company 17-Jul-12 United States
8,216,794 Extracellular serine protease Board of Trustees of the University of Arkansas 10-Jul-12 United States
8,211,647 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 3-Jul-12 Japan
8,232,060 Gene defects and mutant ALK kinase in human solid tumors Cell Signaling Technology, Inc. 31-Jul-12 United States
8,211,666 Sperm-specific cation channel, CATSPER1, and uses therefor Children's Medical Center Corporation 3-Jul-12 United States
8,216,792 Compositions and methods for detection and treatment of proliferative abnormalities associated with overexpression of human transketolase like-1 gene Coy; Johannes 10-Jul-12 Germany
8,227,243 Settings for recombinant adenoviral-based vaccines Crucell Holland B.V. 24-Jul-12 Netherlands
8,216,844 Compositions and methods for improved protein production Danisco US Inc. 10-Jul-12 United States
8,227,200 Methods for identifying kremen polypeptide binding partners Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts 24-Jul-12 Germany
8,211,667 Fungal promoter for expressing a gene in a fungal cell DSM IP Assets B.V. 3-Jul-12 Netherlands
8,232,052 Methods of selecting a dopaminergic neuron proliferative progenitor cells using Lrp4/Corin markers Eisai R&D Management Co., Ltd. 31-Jul-12 Japan
8,216,785 Method for detecting neuroblastoma Fujifilm Corporation 10-Jul-12 Japan
8,232,047 Luciferase signal enhancing compositions Gene Stream Pty Ltd. 31-Jul-12 Australia
8,232,053 EGFR mutations Genentech, Inc. 31-Jul-12 United States
8,232,062 EGFR mutations Genetech, Inc. 31-Jul-12 United States
8,221,991 Orphan nuclear receptor GlaxoSmithKline LLC 17-Jul-12 United States
8,216,833 Cosmid vector Izumu Saito 10-Jul-12 Japan
8,211,683 Plasmid, transformants and process for production of 3- carboxymuconolactone Kabushiki Kaisha Toyota Jidoshokki 3-Jul-12 Japan
8,227,228 D-amino acid oxidase, and method for production of L-amino acid, 2-oxo acid, or cyclic imine Kaneka Corporation 24-Jul-12 Japan
8,232,056 Methods for detecting neovascular age-related macular degeneration Massachusetts Eye and Ear Infirmary 31-Jul-12 United States
8,216,787 Biomarker for successful aging without cognitive decline Medical College of Georgia Research Institute, Inc. 10-Jul-12 United States
8,211,640 Identification of a family of secreted proteins in vascular endothelium Millennium Pharmaceuticals, Inc. 3-Jul-12 United States
8,221,979 Compositions and methods for detecting Noonan syndrome Mount Sinai School of Medicine 17-Jul-12 United States
8,216,821 Regulation of heterologous recombinant protein expression in methylotrophic and methanotrophic bacteria National Research Council of Canada 10-Jul-12 Canada
8,222,004 Diagnosis and treatment of autism using CD38 National University Corporation Kanazawa University 17-Jul-12 Japan
8,227,227 DNase expression in recombinant host cells Novozymes A/S 24-Jul-12 Denmark
8,216,820 Transformant of coryneform bacteria capable of producing isopropanol Research Institute of Innovative Technology for the Earth 10-Jul-12 Japan
8,232,069 Antibody directed against PAP2a and use thereof for diagnostic and therapeutic purposes Sapporo Medical University 31-Jul-12 Japan
8,232,070 DNP63A gene and screening methods of anticancer agent by using it Seoul National University Industry Foundation 31-Jul-12 Korea
8,227,249 Methods and compositions for genomic modification The Board of Trustees of the Leland Stanford Junior University 24-Jul-12 United States
8,227,186 Methods and compositions relating to bioluminescent microorganisms The Ohio State University Research Foundation 24-Jul-12 United States
8,211,645 Recurrent gene fusions in prostate cancer The Regents of the University of Michigan 3-Jul-12 United States
8,227,217 Methods and genetically engineered micro-organisms for the combined production of PDO, BDO and PHP by fermentation Tsinghua University 24-Jul-12 China P. Rep.
8,211,690 Modelling in yeast of the mitochondrial ATP6 gene mutations responsible for NARP syndrome in humans and uses thereof for screening for medicaments Universite Victor Segalen Bordeaux 2 3-Jul-12 France
8,227,194 Monoclonal antibodies with binding specificity for response gene to complement 32 (RGC-32) University of Maryland, Baltimore 24-Jul-12 United States
8,211,646 Methods of treating ovarian cancer by modulating SnoN University of South Florida 3-Jul-12 United States
8,216,781 Gene polymorphisms as predictors of tumor progression and their use in cancer therapy University of Southern California 10-Jul-12 United States
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,229,673 Human metabolic models and methods Genomatica, Inc. 24-Jul-12 United States
8,234,077 Method of selecting genes from gene expression data based on synergistic interactions among the genes The Trustees of Columbia University in the City of New York 31-Jul-12 United States
DRUG
Pat No Title Assignee Date Issued Country
8,227,516 Compounds as histone deacetylase inhibitors 4SC Discovery GmbH 24-Jul-12 Germany
8,221,767 Antigenicity of infectious pancreatic necrosis virus VP2 sub-viral particles expressed in yeast Advanced Bionutrition Corporation 17-Jul-12 United States
8,222,222 Compositions and methods for inhibiting expression of the PCSK9 gene Alnylam Pharmaceuticals, Inc. 17-Jul-12 United States
8,217,017 Modulation of insulin like growth factor I receptor expression Antisense Therapeutics Limited 10-Jul-12 Australia
8,216,998 Treatment of ischemic events Biotempt B.V 10-Jul-12 Netherlands
8,216,782 PTTG1 as a biomarker for cancer treatment Cedars-Sinai Medical Center 10-Jul-12 United States
8,227,441 Methods to increase or decrease bone density Celltech R & D, Inc. 24-Jul-12 United States
8,211,868 Paramyxovirus vector encoding angiogenesis gene and use thereof DNAVEC Research Inc. 3-Jul-12 Japan
8,216,586 Lipases and uses thereof DSM IP Assets B.V. 10-Jul-12 Netherlands
8,221,770 Vaccine compositions comprising L2 and/or L3 immunotype lipooligosaccharides from LGTB-neisseria meningitidis GlaxoSmithKline Biologicals s.a. 17-Jul-12 Belgium
8,227,434 Materials and methods for treating oncological disorders H. Lee Moffitt Cancer Center & Research Institute, Inc. 24-Jul-12 United States
8,231,881 Fusion proteins and their use in the diagnosis and treatment of leishmaniasis Infectious Disease Research Institute 31-Jul-12 United States
8,227,404 Method of preventing acute or sub-acute hepatic failure in a subject by administering a soluble human tumor necrosis factor alpha fusion protein Li; Hai 24-Jul-12 China P. Rep.
8,231,913 Angina pectoris and ischemic heart disease and synergistic phytoceutical composition for same Olalde Rangel; Jose Angel 31-Jul-12 Venezuera
8,227,443 Silencing of CSN5 gene expression using interfering RNA Protiva Biotherapeutics, Inc. 24-Jul-12 Canada
8,216,564 Composite oncolytic herpes virus vectors Ramot At Tel-Aviv University Ltd. 10-Jul-12 Israel
8,227,432 Transposon system and methods of use Regents of the University of Minnesota 24-Jul-12 United States
8,222,210 Methods of using substance P to promote healing of vascular wounds Reid; Ted 17-Jul-12 United States
8,211,945 Carba-sugar amine derivative and glycolipid metabolic disorder treating agent containing the same as active ingredient Seikagaku Corporation 3-Jul-12 Japan
8,222,221 Modulation of gene expression through endogenous small RNA targeting of gene promoters The Board of Regents of the University of Texas System 17-Jul-12 United States
8,216,585 Targeted particles and methods of using the same The Trustees of the University of Pennsylvania 10-Jul-12 United States
8,231,880 Simian subfamily C adenoviruses SAdV-40, -31, and -34 and uses thereof The Trustess of the University of Pennsylvania 31-Jul-12 United States
8,211,422 Chimeric receptor genes and cells transformed therewith The United States of America, as represented by the Secretary, Department of Health and Human Services 3-Jul-12 United States
8,211,432 Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins University of Manitoba 3-Jul-12 Canada
8,211,423 Muscle derived cells for the treatment of cardiac pathologies and methods of making and using the same University of Pittsburgh 3-Jul-12 United States
8,216,573 Process for the fermentative production of antibodies Wacker Chemie AG 10-Jul-12 Germany
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,217,222 Methods for identifying markers for early-stage human cancer, cancer progression and recurrence Anticancer, Inc. 10-Jul-12 United States
8,217,228 Down-regulation and silencing of allergen genes in transgenic peanut seeds Dodo; Hortense W. 10-Jul-12 United States
8,212,112 Gene participating in low temperature germinability in rice and utilization of the same Hokuren Federation of Agricultural Cooperatives 3-Jul-12 Japan
8,232,453 Promoter from sweet potato ran GTPase gene for the high level expression in plant-tissue culture and vector using the same INJE University Industry-Academic Cooperation Foundation 31-Jul-12 Korea
8,227,661 Methods of identifying agents that ameliorate or modulate effects of PRO1328 gene disruptions Lexicon Genetics, Inc. 24-Jul-12 United States
8,217,227 Recombinant DNA constructs and methods for controlling gene expression Monsanto Technology LLC 10-Jul-12 United States
8,232,447 Animal having modification in MGAT2 gene MSD K.K. 31-Jul-12 Japan
8,222,487 Application of ERF genes from Bupleurum kaoi National Tsing Hua University 17-Jul-12 Taiwan
8,217,226 Nucleic acids and proteins associated with galactomannan synthesis in coffee Nestec, S. A. 10-Jul-12 Switzerland
8,222,488 Enhancing expression of value-added genes by transgenic expression of tombusvirus-based P19 gene mutants Texas A&M University System 17-Jul-12 United States
8,232,454 Gene-transfer vector comprising helper-component protease gene of papaya ringspot virus for broad-spectrum virus resistance in crops and use thereof Yeh; Shyi-Dong 31-Jul-12 Taiwan
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,222,370 Nucleophosmin protein (NPM) mutants, corresponding gene sequences and uses thereof Falini; Brunangelo 17-Jul-12 Italy
8,217,138 Anti-inflammatory compounds and uses thereof Yale University 10-Jul-12 United States
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,212,017 Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer Agensys, Inc. 3-Jul-12 United States
8,217,162 siRNA targeting interleukin-1 receptor-associated kinase 4(IRAK4) Dharmacon, Inc. 10-Jul-12 United States
8,222,396 SiRNA targeting proto-oncogene MET Dharmacon, Inc. 17-Jul-12 United States
8,222,395 siRNA targeting kinase insert domain receptor (KDR) Dharmacon, Inc. 17-Jul-12 United States
8,232,386 SiRNA targeting apolipoprotein B (APOB) Dharmacon, Inc. 31-Jul-12 United States
8,232,385 siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) Dharmacon, Inc. 31-Jul-12 United States
8,227,185 Non-M, non-O HIV-1 strains, fragments and uses Institute National de la Sante et de la Recherche Medical-Inserm 24-Jul-12 France
8,222,386 P. pastoris ADH promoter and use thereof to direct expression of proteins Keck Graduate Institute 17-Jul-12 United States
8,232,377 Method for high-level secretory production of protein National Institute of Advanced Industrial Science and Technology 31-Jul-12 Japan
8,222,385 Germ cell marker using fish vasa gene National University Corporation Tokyo University of Marine Science Technology 17-Jul-12 Japan
8,227,587 Dengue chimeric viruses Sanofi Pasteur SA 24-Jul-12 France
8,232,383 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Sirna Therapeutics, Inc. 31-Jul-12 United States
8,232,384 Antisense oligonucleotides for inducing exon skipping and methods of use thereof University of Western Australia 31-Jul-12 Australia
8,232,381 Isolated nucleic acid molecules from transgenic papaya line 18-2-4 resistant to papaya ringspot virus and use thereof Yeh; Shyi-Dong 31-Jul-12 Taiwan
SURGERY
Pat No Title Assignee Date Issued Country
8,221,414 Catheter Boston Scientific Corporation 17-Jul-12 United States
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