DECEMBER, 2013 Gene-Related Patents Issued - Full patent:
Pat No Title Assignee Date Issued Country
8,603,795 Fungal protease and use thereof AB Enzymes Oy 10-Dec-13 Finland
8,609,390 Fungal serine protease and use thereof AB Enzymes Oy 17-Dec-13 Finland
8,614,085 Yeast with increased butanol tolerance involving a multidrug efflux pump gene Butamax(TM) Advanced Biofuels LLC 24-Dec-13 United States
8,603,996 Modular aptamer-regulated ribozymes California Institute of Technology 10-Dec-13 United States
8,609,335 Self-assembled single molecule arrays and uses thereof Callida Genomics, Inc. 17-Dec-13 United States
8,614,058 Molecular prognostic signature for predicting breast cancer metastasis, and uses thereof Celera Corporation 24-Dec-13 United States
8,597,910 DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells Children's Medical Center Corporation 3-Dec-13 United States
8,609,396 Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism CJ Cheiljedang Corporation 17-Dec-13 Korea
8,603,797 Methods and compositions for targeted mutagenesis in bacteria Cornell University 10-Dec-13 United States
8,609,369 Yarrowia peroxisomal 2,4-dienoyl-CoA reductase promoter regions for gene expression in yeast E I du Pont de Nemours and Company 17-Dec-13 United States
8,609,405 GABA neuron progenitor cell marker 65B13 Eisai R&D Management Co., Ltd. 17-Dec-13 Japan
8,597,918 Process of separating components of a fermentation broth Genomatica, Inc. 3-Dec-13 United States
8,609,394 Biotechnological production of chondroitin Gnosis S.p.A. 17-Dec-13 Italy
8,597,942 System for expression of genes in plants iBio, Inc. 3-Dec-13 United States
8,617,845 Sequence diversity generation in immunoglobulins Innovative Targeting Solutions, Inc. 31-Dec-13 Canada
8,597,931 Mutant yeast strains capable of accumulating a large quantity of lipids Institut National de la Recherche Agronomique 3-Dec-13 France
8,603,798 Process for large scale production of plasmid DNA by E. coli fermentation Merck Sharp & Dohme Corp. 10-Dec-13 United States
8,617,875 Expression vector suitable for expression of a coding sequence for gene therapy Mogam Biotechnology Research Institute 31-Dec-13 Korea
8,603,774 Extract of E. coli cells having mutation in ribosomal protein S12, and method for producing protein in cell-free system using the extract National Food Research Institute 10-Dec-13 Japan
8,609,342 Reporter gene assay method Otsuka Pharmaceutical Co., Ltd. 17-Dec-13 Japan
8,603,824 Process for improved protein expression by strain engineering Pfenex, Inc. 10-Dec-13 United States
8,603,814 Method of inhibiting nonsense-mediated mRNA decay Rutgers the State University of New Jersey 10-Dec-13 United States
8,597,877 Polymorphic loci that differentiate Escherichia coli O157:H7 from other strains Seattle Children's Hospital 3-Dec-13 United States
8,597,923 Oxidation of compounds using genetically modified Candida SyntheZyme, LLC 3-Dec-13 United States
8,597,880 Methods and compositions for identifying increased risk of developing fragile X-associated disorders The Fred Hutchinson Cancer Research Center 3-Dec-13 United States
8,617,876 Rhodopsin gene conserved regions in a viral vector enhance expression The Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth 31-Dec-13 Ireland
8,614,094 Compositions and methods for determining genetic polymorphisms in the TMEM216 gene The Regents of the University of California 24-Dec-13 United States
8,617,815 Molecules with effects on cellular development and function The Regents of the University of California 31-Dec-13 United States
8,617,813 Methods for modulating embryonic stem cell differentiation The United States of America as represented by the Secretary of the Department of Health and Human Services 31-Dec-13 United States
8,617,812 Polymorphism in bovine prion protein gene sequence The United States of America, as represented by the Secretary of Agriculture 31-Dec-13 United States
8,603,748 Genetic methods for speciating Campylobacter The United States of America, as represented by the Secretary of Agriculture 10-Dec-13 United States
8,597,883 Biomarkers for cancer-related fatigue and use thereof The United States of America, as represented by the Secretary, Department of Health and Human Services 3-Dec-13 United States
8,597,885 Accelerated progression relapse test University of Notre Dame 3-Dec-13 United States
8,614,060 Methods and compositions for predicting drug responses University of Washington 24-Dec-13 United States
8,597,893 Human phospholipase A2 epsilon Washington University In St. Louis 3-Dec-13 United States
Pat No Title Assignee Date Issued Country
8,598,080 Rice cultivar designated `CL131` Board of Supervisors of Louisiana State University And Agricultural and Mechanical College 3-Dec-13 United States
Pat No Title Assignee Date Issued Country
8,598,136 Baculovirus-mediated transgene expression in both mammalian and insect cells Academia Sinica 3-Dec-13 Taiwan
8,598,139 Lipid formulated dsRNA targeting the PCSK9 gene Alnylam Pharmaceuticals, Inc. 3-Dec-13 United States
RE44,681 Compositions and methods for inhibiting growth of SMAD4-deficient cancers Biogen Idec MA Inc. 31-Dec-13 United States
8,609,626 NLK as a marker for diagnosis of liver cancer and as a therapeutic agent thereof Catholic University Industry Academic Cooperation Foundation 17-Dec-13 Korea
8,603,997 siRNA that inhibits WT1 gene expression and uses thereof Haruo Sugiyama 10-Dec-13 Japan
8,603,480 Human cytomegalovirus neutralizing antibodies and use thereof Institute for Research in Biomedicine 10-Dec-13 United States
8,598,188 Method for predicting therapeutic efficacy of chemotherapy on non-small-cell lung cancer Kinki University 3-Dec-13 United States
8,609,065 Molecules for targeting compounds to various selected organs, tissues or tumor cells Kuik-Romeijn; Petra Van 17-Dec-13 Netherlands
8,618,070 Anti-sense oligonucleotides targeted against exon 9 of IL-23R.alpha. gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases Medical Diagnostic Laboratories, LLC 31-Dec-13 United States
8,603,465 Methods for treatment of polyposis Merck Sharp & Dohme, Corp. 10-Dec-13 United States
8,603,995 dsRNA for treating viral infection Novartis AG 10-Dec-13 Switzerland
8,598,133 Methods for treating pain The Regents of the University of Colorado 3-Dec-13 United States
8,609,108 Gamma-glutamyl transpeptidase attenuated Francisella The Secretary of State for Defence 17-Dec-13 United Kingdom
8,603,459 Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use The Trustees of the University of Pennsylvania 10-Dec-13 United States
8,598,143 Sequence-specific inhibition of small RNA function University of Massachusetts 3-Dec-13 United States
8,603,994 Transcriptional repression leading to Parkinson's disease Valted, LLC 10-Dec-13 United States
8,597,637 Breast cancer therapy using an engineered respiratory syncytial virus Zhang; Weidong 3-Dec-13 United States
Pat No Title Assignee Date Issued Country
8,598,412 Seed specific USP promoters for expressing genes in plants Dow AgroSciecnes, LLC. 3-Dec-13 United States
8,598,413 AAD-1 event DAS-40278-9, related transgenic corn lines, event-specific identification thereof, and methods of weed control involving AAD-1 Dow AgroSciecnes, LLC. 3-Dec-13 United States
8,598,409 Non-human organism comprising a gene expression modulation system encoding a chimeric retinoid X receptor Intrexon Corporation 3-Dec-13 United States
8,604,275 Constitutive translationally controlled tumor protein (TCTP) promoter from oil palm type 2 Malaysian Palm Oil Board 10-Dec-13 Malaysia
8,614,370 Nucleic acid sequences from Diabrotica virgifera virgifera leconte and uses thereof Monsanto Technology LLC 24-Dec-13 United States
8,609,934 In vivo assembly of transcription units Monsanto Technology LLC 17-Dec-13 United States
8,604,276 Switchgrass ubiquitin promoter (PVUBI2) and uses thereof University of Tennessee Research Foundation 10-Dec-13 United States
8,609,928 Squash leaf curl virus (SLCV) resistance in cucurbits Vilmorin & Cie 17-Dec-13 France
Pat No Title Assignee Date Issued Country
8,604,169 Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer Agensys, Inc. 10-Dec-13 United States
8,609,819 Extracellular serine protease Board of Trutees of the University of Arkansas 17-Dec-13 United States
8,604,173 Dopaminergic neuron progenitor cell marker 187A5 Eisai R&D Management Co., Ltd. 10-Dec-13 Japan
Pat No Title Assignee Date Issued Country
8,598,333 SiRNA silencing of genes expressed in cancer Alnylam Pharmaceuticals, Inc. 3-Dec-13 United States
8,604,176 Protein-responsive RNA control devices and uses thereof California Institute of Technology 10-Dec-13 United States
8,598,330 CC2D2A gene mutations associated with joubert syndrome and diagnostic methods for identifying the same Centre for Addiction and Mental Health 3-Dec-13 Canada
8,604,183 Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Isis Pharmaceuticals, Inc. 10-Dec-13 United States
8,618,273 Partial fragment of REIC/Dkk-3 gene and cancer therapeutic agent comprising the same Kumon; Hiromi 31-Dec-13 Japan
8,609,830 Methods and compositions for RNA interference Merck Sharp & Dohme Corp. 17-Dec-13 United States
8,618,277 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Merck Sharp & Dohme Corp. 31-Dec-13 United States
8,598,328 Tol1 factor transposase and DNA introduction system using the same National University Corporation Nagoya University 3-Dec-13 Japan
8,604,180 DNA fragment having promoter function Research Institute of Innovative Technology for the Earth 10-Dec-13 Japan
Pat No Title Assignee Date Issued Country
8,618,304 Acylamino-substituted cyclic carboxylic acid derivatives and their use as pharmaceuticals Sanofi 31-Dec-13 France
8,614,305 Nonviral gene delivery vector iopamidol, protamine, ethiodized oil reagent (VIPER) The Board of Trustees of the Leland Stanford Junior University 24-Dec-13 United States
8,604,179 Nucleic acid comprising chimeric gene derived from hepatitis C virus Toray Industries, Inc. 10-Dec-13 Japan
8,609,831 RNA-mediated gene modulation University of Southern California 17-Dec-13 United States
Pat No Title Assignee Date Issued Country
8,597,913 Method of constructing an expression cassette comprising regulatory sequences of a target gene of a plant for expressing gene products Syngenta Participations AG 3-Dec-13 Switzerland
Pat No Title Assignee Date Issued Country
8,620,423 Methods for thermal modulation of nerves contributing to renal function Medtronic Ardian Luxembourg S.a.r.l. 31-Dec-13 Luxembourg
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