DECEMBER, 2012 Gene-Related Patents Issued - Full patent: http://patft.uspto.gov/netahtml/PTO/srchnum.htm
ANIMAL HUSBANDRY
Pat No Title Assignee Date Issued Country
8,327,803 Method for processing a large number of fish eggs Hashimoto Electronic Industry Co., Ltd. 11-Dec-12 Japan
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,338,162 Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium Anaeropharma Science, Inc. 25-Dec-12 Japan
8,323,897 Multiplex amplification of polynucleotides Applied Biosystems, LLC 4-Dec-12 United States
8,323,952 Alcoholic xylose fermentation at high temperatures by the thermotolerant yeast Hansenula polymorpha Archer Daniels Midland Company 4-Dec-12 United States
8,329,448 Yeast host, transformant and method for producing heterologous proteins Asahi Glass Company, Limited 11-Dec-12 United States
8,334,137 MN gene and protein Bayer Healthcare LLC 18-Dec-12 United States
8,338,179 Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product Boehringer Ingelheim Pharma GmbH & Co. KG 25-Dec-12 Germany
8,329,434 Enhanced promoter and method for producing L-lysine using the same CJ Cheiljedang Corporation 11-Dec-12 Korea
8,323,935 Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production E I du Pont de Nemours and Company 4-Dec-12 United States
8,323,960 Ammonium transporter promoters for gene expression in oleaginous yeast E I du Pont de Nemours and Company 4-Dec-12 United States
8,334,126 Coryneform host-vector systems comprising a chromosomal ALR gene which is attenuated or eliminated and methods of using Evonik Degussa GmbH 18-Dec-12 Germany
8,329,398 Universal amplification of fragmented RNA Genomic Health, Inc. 11-Dec-12 United States
8,329,420 Screening method for a substance that binds to an intracellular region of TLR4 Hiroshima University 11-Dec-12 Japan
8,334,129 Microorganism capable of producing polyhydroxyalkanoate, polyhydroxyalkanoate synthase, and gene encoding the same Hitachi Chemical Co., Ltd. 18-Dec-12 Japan
8,329,429 Method of enhancing recombinant protein production Induce Biologics Inc. 11-Dec-12 United States
8,338,168 Chimeric glycoproteins and pseudotyped lentiviral vectors Institut National de la Sante et de la Recherche Medicale 25-Dec-12 France
8,329,430 Polymyxin synthetase and gene cluster thereof Korea Research Institute of Bioscience and Biotechnology 11-Dec-12 Korea
8,323,926 Gene from Hancenula polymorpha capable of controlling unfolded protein response and method for increasing effect of secretion using the same Korea Research Institute of Bioscience and Biotechnology 4-Dec-12 Korea
8,329,463 RNA interference mediating small RNA molecules Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V. 11-Dec-12 Germany
8,334,111 Human diacylglycerol acyltransferase 2 (DGAT2) family members and uses therefor Millennium Pharmaceuticals, Inc. 18-Dec-12 United States
8,329,472 Gene associated with foam formation in acetic acid bacterium, acetic acid bacterium modified to reduce foam formation, and a method for producing vinegar by culturing an acetic acid bacterium modified to reduce foam formation Mizkan Group Corporation 11-Dec-12 Japan
8,334,139 Plasmids for transforming plant cells Monsanto Technology LLC 18-Dec-12 United States
8,323,898 Method for identifying pathogenic microorganisms responsible for infection by extracting the DNA of a microorganism National University Corporation University of Toyama 4-Dec-12 Japan
8,329,426 High throughput method for measuring total fermentables in small amount of plant part Pioneer Hi-Bred International, Inc. 11-Dec-12 United States
8,329,462 Methods and compositions relating to improved lentiviral vectors and their applications Research Development Foundation 11-Dec-12 United States
8,338,107 Method for producing polymers having a preselected activity Scripps Research Institute 25-Dec-12 United States
8,338,099 Reference genes for the normalization of gene expression analysis data SIRS-Lab GmbH 25-Dec-12 Germany
8,323,893 Administration of exogenous miRNA or siRNA Sloan-Kettering Institute for Cancer Research 4-Dec-12 United States
8,323,896 Epidermal growth factor (EGF) expression and/or polymorphisms thereof for predicting the risk of developing cancer The General Hospital Corporation 4-Dec-12 United States
8,338,138 Methods for making and using molecular switches involving circular permutation The John Hopkins University 25-Dec-12 United States
8,334,124 Modified Aspergillus niger phytase The United States of America as represented by the Secretary of Agriculture 18-Dec-12 United States
8,334,101 Intracellular DNA receptor University of Massachusetts 18-Dec-12 United States
8,323,963 Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease University of Southern California 4-Dec-12 United States
8,334,096 Methods and compositions related to arrhythmogenic right ventricular cardiomyopathy (ARVC) Washington State University Research Foundation 18-Dec-12 United States
8,338,098 Methods and compositions for improved cattle longevity and milk production Wisconsin Alumni Research Foundation 25-Dec-12 United States
8,338,147 Process for producing D-mannitol zuChem, Inc. 25-Dec-12 United States
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,332,159 Method for enhancing efficacy of preparation of monoclonal antibody Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 11-Dec-12 Japan
8,326,547 Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm Nanjingjinsirui Science & Technology Biology Corp. 4-Dec-12 China P. Rep.
8,332,157 Information processing apparatus, information processing method, and program Sony Corporation 11-Dec-12 Japan
DRUG
Pat No Title Assignee Date Issued Country
8,334,273 Compositions and methods for inhibiting expression of factor VII gene Alnylam Pharmaceuticals, Inc. 18-Dec-12 United States
8,329,636 Carcinoma diagnosis and treatment, based on ODC1 genotype Arizona Board of Regents on Behalf of University of Arizona 11-Dec-12 United States
8,334,271 Use of VEGF in the treatment of retarded fetal growth in pregnancy Ark Therapeutics, Ltd. 18-Dec-12 United Kingdom
8,329,162 Targeted gene delivery for dendritic cell vaccination California Institute of Technology 11-Dec-12 United States
8,329,641 Remedies for ischemic disease of the limbs comprising administration of G-CSF Chugai Seiyaku Kabushiki Kaisha 11-Dec-12 Japan
8,338,474 Use of phthalimide and/or sulphonamide derivatives in the treatment of diseases which require reducing the TNF-.alpha. levels and an exogenous source of nitric oxide, phthalimide derivatives, sulphonamide derivatives, and a method for obtaining a sulphonamide derivative Dos Santos; Jean Leandro 25-Dec-12 Brazil
8,323,659 Method for diagnosing and/or treating tumor Keio University 4-Dec-12 Japan
8,329,670 System for delivering nucleic acids for suppressing target gene expression by utilizing endogenous chylomicron National University Corporation Tokyo Medical and Dental University 11-Dec-12 Japan
8,334,272 Methods for nucleic acid transfer into cells Northwestern University 18-Dec-12 United States
8,337,812 Regulator of ephrin-Eph receptor signaling and mouse having abnormal ephrin-Eph receptor signaling mechanisms RIKEN 25-Dec-12 Japan
8,338,366 Bioactive FUS1 peptides and nanoparticle-polypeptide complexes The Board of Regents of the University of the Texas System 25-Dec-12 United States
8,334,275 Cellular genes regulated by HIV-1 infection and methods of use thereof The Children's Hospital of Philadelphia 18-Dec-12 United States
8,329,177 Method of treating hypertrophic cardiomyopathy The John Hopkins University 11-Dec-12 United States
8,323,664 Live vaccine strains of Francisella The Secretary of State for Defence 4-Dec-12 United Kingdom
8,337,831 Live, oral vaccine for protection against Shigella dysenteriae serotype 1 The United States of America, as Represented by the Secrectary, Department of Health and Human Services 25-Dec-12 United States
8,323,706 Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis The United States of America, as represented by the Secretary of Agriculture 4-Dec-12 United States
8,338,386 Prevention/treatment of ichthyosis vulgaris, atopy and other disorders University Court of the University of Dundee 25-Dec-12 United Kingdom
8,323,618 Ultrasmall superparamagnetic iron oxide nanoparticles and uses thereof University of Houston System 4-Dec-12 United States
8,329,681 Methods and compositions for the efficient delivery of therapeutic agents to cells and animals University of Massachusetts 11-Dec-12 United States
8,334,274 Immunomodulation of inflammatory conditions utilizing Follistatin-like Protein-1 and agents that bind thereto University Of Pittsburg--Of The Commonwealth of Higher Education 18-Dec-12 United States
8,337,829 Conditioned medium and proliferated cell lines produced therefrom University of South Florida 25-Dec-12 United States
8,324,148 Compositions for importing biologically active molecules into cells Vanderbilt University 4-Dec-12 United States
8,338,385 Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor ViroMed Co., Ltd. 25-Dec-12 Korea
8,338,456 Cut-point in PTEN protein expression that accurately identifies tumors and is predictive of drug response to a pan-ErbB inhibitor Wyeth LLC 25-Dec-12 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,329,995 Soybeans with reduced isoflavones Arcadia Biosciences, Inc. 11-Dec-12 United States
8,329,988 Method for increasing pathogen resistance in transgenic plants BASF Plant Science GmbH 11-Dec-12 Germany
8,330,006 Maize with good digestibility and disease resistant Biogemma 11-Dec-12 France
8,324,456 Method for improving transformation efficiency using powder Japan Tobacco Inc. 4-Dec-12 Japan
8,338,664 Nucleic acid molecules encoding plant proteins in the C3HC4 family and methods for the alteration of plant cellulose and lignin content Monsanto Do Brasil LTDA. 25-Dec-12 Brazil
8,329,990 Crop grain filling gene GIF1 and the applications thereof Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 11-Dec-12 China P. Rep.
8,334,427 Induction of Xa27 by the avrXa27 gene in rice confers broad-spectrum resistance to Xanthomonas oryzae pv. oryzae and enhanced resistance to Xanthomonas oryzae pv. oryzicola Temasek Life Sciences Laboratory 18-Dec-12 Singapore
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,324,368 GNAQ targeted dsRNA compositions and methods for inhibiting expression Alnylam Pharmaceuticals, Inc. 4-Dec-12 United States
8,334,373 Nuclease resistant double-stranded ribonucleic acid Alnylam Pharmaceuticals, Inc. 18-Dec-12 United States
8,324,366 Compositions and methods for delivering RNAI using lipoproteins Alnylam Pharmaceuticals, Inc. 4-Dec-12 United States
8,324,181 Modulation of gene expression by oligomers targeted to chromosomal DNA Board of Regents, The University of Texas System 4-Dec-12 United States
8,329,882 Genetic control of mammalian cells with synthetic RNA regulatory systems California Institute of Technology 11-Dec-12 United States
8,334,374 Methods and means for obtaining modified phenotypes Commonwealth Scientific and Industrial Research Organisation 18-Dec-12 Australia
8,324,365 Conjugate for gene transfer comprising oligonucleotide and hydrophilic polymer, polyelectrolyte complex micelles formed from the conjugate, and methods for preparation thereof Korea Advanced Institute of Science and Technology 4-Dec-12 Korea
8,324,363 Microarray for detection of the deletion of exon 3 of the G-CSF gene Lee; Sang Yup 4-Dec-12 Korea
8,324,367 Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity Medtronic, Inc. 4-Dec-12 United States
8,338,578 Cystic fibrosis gene mutations Quest Diagnostics Investments Incorporated 25-Dec-12 United States
8,329,888 Small internally segmented interfering RNA Santaris Pharma A/S 11-Dec-12 Denmark
8,329,889 In vivo gene sensors Trustees of Boston University 11-Dec-12 United States
8,329,892 Methods and compositions for enhancing the efficacy and specificity of RNA silencing University of Massachusetts 11-Dec-12 United States
8,338,643 Reagent for introduction of protein or gene Waseda University 25-Dec-12 Japan
SURGERY
Pat No Title Assignee Date Issued Country
8,326,416 Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue Impulse Dynamics NV 4-Dec-12 Netherlands
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