APRIL 2012 Gene-Related Patents Issued - Full patent
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,153,431 Compositions and methods for making mutations in cell lines and animals ABT Holding Company 10-Apr-12 United States
8,158,352 Screening of a novel hepatic syndrome and its uses Assistance Publique-Hopitaux de Paris 17-Apr-12 France
8,158,595 Modular aptamer-regulated ribozymes California Institute of Technology 17-Apr-12 United States
8,148,073 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 3-Apr-12 Japan
8,158,350 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 17-Apr-12 Japan
8,148,063 Probe, probe set, probe-immobilized carrier, and genetic testing method Canon Kabushiki Kaisha 3-Apr-12 Japan
8,163,483 Compositions and methods for spinocerebellar ataxia Cedars-Sinai Medical Center 24-Apr-12 United States
8,158,416 CDNA corresponding to the antigenome of nonsegmented negative strand RNA viruses, and process for the production of such viruses encoding additional antigenically active proteins Crucell Switzerland AG 17-Apr-12 Switzerland
8,158,362 Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype deCODE Genetics ehf. 17-Apr-12 Island
8,158,391 Production of an .alpha.-carboxyl-.omega.-hydroxy fatty acid using a genetically modified Candida strain DNA Twopointo, Inc. 17-Apr-12 United States
8,148,098 Methods of cleaving DNA with rationally-designed meganucleases Duke University 3-Apr-12 United States
8,163,514 Methods of cleaving DNA with rationally-designed meganucleases Duke University 24-Apr-12 United States
8,163,521 Self-assembled proteins and related methods and protein structures Duquesne University of the Holy Ghost 24-Apr-12 United States
8,153,404 Alleles of the zwf gene from coryneform bacteria Evonik Degussa GmbH 10-Apr-12 Germany
8,163,492 Microfluidic device and methods of using same Fluidign Corporation 24-Apr-12 United States
8,148,072 Method of profiling gene expression in a subject having heart failure GeneNews Corporation 3-Apr-12 United States
8,148,076 Gene expression profiling of EGFR positive cancer Genomic Health, Inc. 3-Apr-12 United States
8,158,384 Methods for reducing or eliminating .alpha.-mannosidase resistant glycans in the production of glycoproteins Glycofi, Inc. 17-Apr-12 United States
8,148,136 Diagnostics and vaccines for mycobacterial infections of animals and humans HAV Vaccines Limited 3-Apr-12 United Kingdom
8,153,433 Mammalian cell lines for increasing longevity and protein yield from a cell culture Immunomedics, Inc. 10-Apr-12 United States
8,153,413 High alkaline protease and use thereof Japan Agency for Marine-Earth Science and Technology 10-Apr-12 Japan
8,153,362 Mitochondrial function of prohibitin 2 (PHB2) Jichi Medical University 10-Apr-12 Japan
8,163,525 Method of expressing long-chain prenyl diphosphate synthase Kaneka Corporation 24-Apr-12 Japan
8,163,482 BBS10 related diagnostic methods for Bardet-Biedl syndrome Katsanis; Nicholas 24-Apr-12 United States
8,148,137 Mutant microorganism having improved production ability of branched amino acid and method for preparing branched amino acid using the same Korea Advanced Institute of Science & Technology 3-Apr-12 Korea
8,148,143 Method and composition for genetically modifying non-human cells and animals Kwang-Hua Development and Investment Ltd. 3-Apr-12 Hong Kong
8,163,553 Human trophoblast stem cells and use thereof Lee; Jau-Nan 24-Apr-12 Taiwan
8,163,473 Method for using DNA repair capacity as a biomarker of breast cancer risk in women Matta Murias; Jaime L. 24-Apr-12 France
8,153,402 Emulsion compositions Medical Research Council 10-Apr-12 United Kingdom
8,163,506 Use of toll-like receptor-expressing cells Meiji Co., Ltd. 24-Apr-12 Japan
8,148,119 Hydroxylase gene and use thereof Microbiopharm Japan Co., Ltd. 3-Apr-12 Japan
8,153,364 Emulsion compositions MRC 10-Apr-12 United Kingdom
8,148,144 pCryptoRNAi National University Corporation Chiba University 3-Apr-12 Japan
8,153,358 Selection and enrichment of proteins using in vitro compartmentalization New England Biolabs, Inc. 10-Apr-12 United States
8,158,360 Effects of inhibitors of FGFR3 on gene transcription Novartis AG 17-Apr-12 Switzerland
8,163,524 Comparative analysis of extracellular RNA species OncoMedx, Inc. 24-Apr-12 United States
8,148,080 Gene and protein relating to hepatocellular carcinoma and methods of use thereof Oncotherapy Science, Inc. 3-Apr-12 Japan
8,158,361 Tumor marker Qiagen GmbH 17-Apr-12 Germany
8,153,385 Target protein and target gene in drug designing and screening method Reverse Proteomics Research Institute Co., Ltd 10-Apr-12 Japan
8,158,351 Method for determining inflammatory disease Riken 17-Apr-12 Japan
8,153,399 Methods and compositions for inactivating glutamine synthetase gene expression Sangamo Biosciences, Inc. 10-Apr-12 United States
8,163,478 Fertility restoration for Ogura cytoplasmic male sterile Brassica and method Syngenta Participations AG 24-Apr-12 Switzerland
8,158,355 Method to generate or determine nucleic acid tags corresponding to the terminal ends of DNA molecules using sequences analysis of gene expression (terminal SAGE) The Agency For Science, Technology and Research 17-Apr-12 Singapore
8,153,372 Method for simultaneously determining in a single multiplex reaction gender of donors and quantities of genomic DNA and ratios thereof, presence and extent of DNA degradation, and PCR inhibition within a human DNA sample The Board of Regents for Oklahoma State University 10-Apr-12 United States
8,163,476 CUDR as biomarker for cancer progression and therapeutic response The Chinese University of Hong Kong 24-Apr-12 China P. Rep.
8,163,505 Methods using PBK1 for identifying agents that treat metabolic disorders The Penn State Research Foundation 24-Apr-12 United States
8,148,124 Regulation of gene expression by protein methylation The Regents of the University of California 3-Apr-12 United States
8,148,129 Generation of potent dominant negative transcriptional inhibitors The Regents of the University of California 3-Apr-12 United States
8,148,060 Recombinant viral vector for gene transfer into lymphoid cells The Research Foudation for Microbial Diseases of Osaka University 3-Apr-12 Japan
8,153,376 Means and methods for diagnosing and/or treating a subject at risk of developing heart failure Universiteit Maastricht 10-Apr-12 United States
8,153,366 Methods and compositions for predicting drug responses University of Washington 10-Apr-12 United States
8,148,102 Sequences for FK228 biosynthesis and methods of synthesizing FK228 and FK228 analogs UWM Research Foundation, Inc. 3-Apr-12 United States
8,153,368 Four-jointed box (FJX1) in cancer diagnosis and treatment Vanderbilt University 10-Apr-12 United States
8,153,403 Process for identifying existence of single nucleotide polymorphism without DNA sequencing Zainiev; Gafur 10-Apr-12 United States
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,160,854 Method of managing and displaying gene expression data Hitachi Software Engineering Co., Ltd. 17-Apr-12 Japan
8,150,625 System and method for classifying a body tissue sample Yissum Research Development Company of the Hebrew University of Jerusalem 3-Apr-12 Israel
DRUG
Pat No Title Assignee Date Issued Country
8,148,344 Compositions and methods for mediating RNAi in vivo Alnylam Pharmaceuticals, Inc. 3-Apr-12 United States
8,163,711 Compositions and methods for inhibiting expression of the HAMP gene Alnylam Pharmaceuticals, Inc. 24-Apr-12 United States
8,163,280 Antibodies to c-Met Amgen Fremont Inc 24-Apr-12 United States
8,147,820 Attenuated vaccine against fish pathogen Francisella sp Board of Supervisors of Louisiana State University And Agricultural and Mechanical College 3-Apr-12 United States
8,147,827 Tumor treatment Genentech, Inc. 3-Apr-12 United States
8,148,345 Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA Georgia Health Sciences University Research Institute, Inc. 3-Apr-12 United States
8,153,138 Recombinant MVA virus GSF-Forschungszentrum fur Umwelt und Gesundheit GmbH 10-Apr-12 Germany
8,158,600 Methods and compositions for detecting and treating retinal diseases based on metargidin (ADAM-15) Inana; George 17-Apr-12 United States
8,148,343 Tumor suppressor factor Molecular Discovery Systems 3-Apr-12 Australia
8,148,342 Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases Quark Pharmaceuticals Inc. 3-Apr-12 United States
8,158,596 Materials and methods for FOXP3 tumor suppression The Regents of the University of Michigan 17-Apr-12 United States
8,147,823 Method of treating or retarding the development of blindness The Trustees of the University of Pennsylvania 3-Apr-12 United States
8,147,803 Ultrasmall superparamagnetic iron oxide nanoparticles and uses thereof The University of Houston 3-Apr-12 United States
8,153,110 Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle The University of Tokyo 10-Apr-12 Japan
8,153,116 Use of conditional plasmodium strains lacking an essential gene in malaria vaccination University of Connecticut 10-Apr-12 United States
8,153,155 Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery system University of Utah 10-Apr-12 United States
8,153,154 Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery systems University of Utah 10-Apr-12 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,148,600 Immunocompromised rodents as dual color tumor models Anticancer, Inc. 3-Apr-12 United States
8,153,861 Genes for improving salt tolerance and drought tolerance of plant and the uses thereof Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences 10-Apr-12 China P. Rep.
8,163,977 Extra-cellular matrix localized ferritin for iron uptake, storage, and stress tolerance Chakraborty; Niranjan 24-Apr-12 India
8,148,605 Biological systems input-output response system and plant sentinels Colorado State University Research Foundation 3-Apr-12 United States
8,148,608 Systems and methods for clonal expression in plants Fraunhofer USA, Inc 3-Apr-12 United States
8,153,862 Cytochrome P450 gene for increasing seed size or water stress resistance of plant Myongji University Industry and Academia Cooperation 10-Apr-12 Korea
8,148,601 Rice blast susceptibility gene Pi21, resistance gene pi21, and uses thereof National Institute of Agrobiological Sciences 3-Apr-12 Japan
8,153,858 Sale of fluorescent transgenic ornamental fish National University of Singapore 10-Apr-12 Singapore
8,148,604 Methods and materials for conferring resistance to pests and pathogens of plants Venganza Inc. 3-Apr-12 United States
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,158,754 Multiple modified derivatives of gelatin and crosslinked material thereof Bioregen Biomedical (Changzhou) Co., Ltd. 17-Apr-12 China P. Rep.
8,163,883 Gene encoding labyrinthin, a marker for cancer Mission Therapeutics, Inc. 24-Apr-12 United States
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,158,769 Members of the capsaicin/vanilloid receptor family of proteins and uses thereof Bayer Schering Pharma Aktiengesellschaft 17-Apr-12 Germany
8,163,709 TAK1-D mediated induction of cell death in human cancer cells by specific sequence short double-stranded RNAS Board of Regents of the University of Texas System 24-Apr-12 United States
8,153,776 Methods and compositions for RNA interference Cold Spring Harbor Laboratory 10-Apr-12 United States
8,158,344 Methods and compositions for correlating genetic markers with multiple sclerosis Duke University 17-Apr-12 United States
8,153,602 Composition and methods for the pulmonary delivery of nucleic acids Isis Pharmaceuticals, Inc. 10-Apr-12 United States
8,153,778 RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA) Merck Sharp & Dohme Corp. 10-Apr-12 United States
8,158,772 Oligonucleotide sequences that identify species of animal National Institute of Agrobiological Sciences 17-Apr-12 Japan
8,163,894 DNA for eukaryotic expression of CymR National Research Council of Canada 24-Apr-12 Canada
8,148,514 hTERT gene expression regulatory gene National University Corporation Tottori University 3-Apr-12 Japan
8,148,513 hTERT gene expression regulatory gene National University Corporation Tottori University 3-Apr-12 Japan
8,163,892 Oncolytic virus replicating selectively in tumor cells Oncolys Biopharma, Inc. 24-Apr-12 Japan
8,163,893 Pseudotyped retroviral vectors and methods of use thereof The Regents of the University of Caifornia 24-Apr-12 United States
8,158,766 Genes with ES cell-specific expression Yamanaka; Shinya 17-Apr-12 Japan
SURGERY
Pat No Title Assignee Date Issued Country
8,150,520 Methods for catheter-based renal denervation Ardian, Inc. 3-Apr-12 United States
8,150,519 Methods and apparatus for bilateral renal neuromodulation Ardian, Inc. 3-Apr-12 United States
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